Endocrine Abstracts

Introduction: Type 2 diabetes represents an important health problem and is designated by a progressive course. Since the vast majority of type 2 diabetic patients are overweight, there is a need not only to avoid weight gain but to lower body weight. Therefore, the usage of drugs that have the potential to lower body weight (GLP1 RA and SGLT2 -inhibitors) should with metformin be preferred initial therapy in the obese and overweight type 2 diabetic patients.<p class="abst...

Introduction: Type 2 diabetes represents an important health problem and is designated by a progressive course, and the subsequent long-term insulin therapy to achieve optimal glucose control. It is important to stress that a substantial number of patients do not achieve optimal glucose control despite the usage of two doses of premixed insulin. Detemir insulin, along with a low pharmacodynamic coefficient of variability, exhibits anorexigenic features, through its effects on ...

: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of reproductive age. It’s a heterogeneous functional disorder of unclear etiology. The features of PCOS are disorders of ovulation, androgen excess, polycystic ovaries; it’s associated with presence of associated risk factors for cardiovascular disease (obesity, glucose intolerance, dyslipidemia). The diagnosis of PCOS is made using the Rotterdam 2003 criteria. 23yo female patie...

Objective: To analyse the semen quality in patients with newly diagnosed non-Hodgkin lymphoma before starting the treatment.Materials and methods: We evaluated semen quality in 29 patients with non-Hodgkin lymphoma who underwent sperm banking in our clinic over a 9-year period. Semen samples were collected by masturbation after 2–7 days of sexual abstinence. Age at banking, semen volume, sperm concentration, and total and progressive sperm motility ...

In order to compare effects of treatment in hyperthyroid patients treated with thyrostatic drug alone and those treated with thyrostatic plus levothyroxine we reviewed data from 60 consecutive patients attending our outpatient clinic. 27 patients, 25 ♀ and 2 ♂, aged 27–68 years were treated with thyrostatic drug alone, while 33 patients, 31 ♀ and 2 ♂, aged 19–88 years received thyrostatic plus levothyroxine. Number of remissions was greate...

We retrospectively collected data from 62 pregnant females who were followed for hyperthyroidism (n=17), hypothyroidism (n=21), euthyroid Hashimoto’s thyroiditis (n=9), and simple goitre and other non-autoimmune thyroid diseases (n=15).Among them 33 showed at least once during pregnancy low FT4, or low FT3 and FT4 in total on 74 occasions. Low FT4 was found on 15, low FT3 on 15 and low FT<s...

Last 10 years, we are living in iodine sufficient environment. To clarify natural course of thyroid autonomy in this conditions, we investigated 100 consecutive patients in last three months – 93 female and 7 male aged 19–86 years. Included were patients with scans showing thyroid autonomy, and patients with nodular or diffuse goiter with low or suppressed TSH. We followed them from their first visit. Thirty patients were hyperthyroid – one spontaneously cured, ...

Objective: To analyse the semen quality in patients with newly diagnosed lymphoma’s before starting the treatment.Materials and methods: We evaluated semen quality in 131 patient with lymphoma who underwent sperm banking in our clinic over a 14-year period. 102 patients had Hodgkin’s lymphoma, and 29 had non-Hodgkin’s lymphoma. Semen samples were collected by masturbation after 2–7 days of sexual abstinence. Age at banking, semen volu...